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KSHV 2020 marks the first time the conference is being held in Africa since the discovery of the Kaposi's Sarcoma Herpesvirus twenty-five years ago. Our objective is to bring together a diverse audience of researchers and clinicians, especially those on the ground in Africa who are encountering HIV-associated diseases daily, to facilitate the conduct of both translational and basic research on KSHV and KS, to foster new collaborations, and to explore novel therapeutic strategies for treating patients with ailments associated with KSHV in diverse populations and geographics. The meeting will be held in Dar es Salaam, Tanzania, from June 22nd through June 25th including the opportunity to visit the Ocean Road Cancer Institute with our local host, Dr. Julius Mwaiselage. The conference will be followed by a dedicated networking and training workshop on Friday, June 26th focused on engaging and collaborating with African investigators.